BDBM50217610 4-(2-(4-(methylsulfinyl)phenyl)-4-(naphthalen-2-yl)-1H-imidazol-5-yl)pyridine::4-[2-(4-Methanesulfinyl-phenyl)-5-naphthalen-2-yl-3H-imidazol-4-yl]-pyridine::CHEMBL17023

SMILES CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc2ccccc2c1)-c1ccncc1

InChI Key InChIKey=IJEKVOJHPYSPSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217610   

TargetAngiopoietin-1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50217610(4-(2-(4-(methylsulfinyl)phenyl)-4-(naphthalen-2-yl...)
Affinity DataIC50: 300nMAssay Description:Inhibition of Tie2 kinase by autophosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50217610(4-(2-(4-(methylsulfinyl)phenyl)-4-(naphthalen-2-yl...)
Affinity DataIC50: 770nMAssay Description:Inhibitory activity against interleukin-1 (IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article