BDBM50217489 (R)-N-(1-(cyclopropylmethyl)-2-oxoazepan-3-yl)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamide::CHEMBL234989

SMILES O=C(N[C@@H]1CCCCN(CC2CC2)C1=O)N1CCC(CC1)N1Cc2ccccc2NC1=O

InChI Key InChIKey=LWPQGRUYRXAUBV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217489   

LigandPNGBDBM50217489((R)-N-(1-(cyclopropylmethyl)-2-oxoazepan-3-yl)-4-(...)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50217489((R)-N-(1-(cyclopropylmethyl)-2-oxoazepan-3-yl)-4-(...)
Affinity DataKi:  7.80E+3nMAssay Description:Displacement of [125I]CGRP from human CL receptor in RAMP1 membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed