BDBM50216823 2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoethyl]butyl}-1,2,4-oxadiazol-3-yl)isonicotinic acid::CHEMBL226853

SMILES ONC(=O)C[C@@H](CCCC1CCCCC1)c1nc(no1)-c1cc(ccn1)C(O)=O

InChI Key InChIKey=BCLDMTLBRZOHBQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50216823   

TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216823(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216823(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216823(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetZinc metalloproteinase dpy-31(Brown stomach worm)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50216823(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of recombinant Teladorsagia circumcincta DPY-31 astacin domain expressed in Escherichia coli using Suc-Ala-Ala-Ala-pNA as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetZinc metalloproteinase dpy-31(Filarial nematode worm)
University of Glasgow

Curated by ChEMBL
LigandPNGBDBM50216823(2-(5-{(1R)-4-cyclohexyl-1-[2-(hydroxyamino)-2-oxoe...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Brugia malayi DPY-31 astacin domain expressed in Escherichia coli using Suc-Ala-Ala-Ala-pNA as substrate preincubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed