BDBM50216464 CHEMBL146048

SMILES Cc1nc(SCc2ccc(cc2)-c2ccccc2-c2nn[nH]n2)c2ccccc2n1

InChI Key InChIKey=SAVLZXIXHKYUSD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216464   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50216464(CHEMBL146048)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory effect in cAMP-specific Phosphodiesterase 4 (PDE 4) isolated from guinea pig ventricular tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2018
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50216464(CHEMBL146048)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibitory effect in cGMP-inhibited Phosphodiesterase 3 (PDE 3) isolated from guinea pig ventricular tissue.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2018
Entry Details Article
PubMed
LigandPNGBDBM50216464(CHEMBL146048)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PDE7 catalytic domain (unknown origin) using [3H]-cAMP as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed