BDBM50215545 CHEMBL6338

SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O

InChI Key InChIKey=NEZDQSKPNPRYAW-UHFFFAOYSA-N

Data  2 KI  13 IC50  1 Kd  1 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50215545   

TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 760nMAssay Description:Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293T cells and using 5-FAM labelled-EA2 peptide as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 using Muc5AC peptide as substrate incubated for 30 mins by HPLC-based en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 using Muc2 peptide as substrate incubated for 30 mins by HPLC-based enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of catalytic activity of ppGalNAcT1 (unknown origin) using EA2 peptide as substrate incubated for 30 mins by HPLC-based enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataKon:  0.00104M-1s-1Assay Description:Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as dissociation rate by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataKoff:  3.53E+3s-1Assay Description:Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as association rate by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 using Muc7 peptide as substrate incubated for 30 mins by HPLC-based enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 6(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of catalytic activity of ppGalNAcT6 (unknown origin) using EA2 peptide as substrate incubated for 30 mins by HPLC-based enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 4.99E+5nMAssay Description:Inhibition of DNA gyrase supercoiling in Escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 3.12E+3nMAssay Description:Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 W282A mutant expressed in HEK293 cells using EA2 peptide as substrate by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of catalytic activity of OGT (unknown origin) using EA2 peptide as substrate incubated for 30 mins by HPLC-based enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 10(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 330nMAssay Description:Inhibition of catalytic activity of ppGalNAcT10 (unknown origin) using EA2 peptide as substrate incubated for 30 mins by HPLC-based enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 3(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of catalytic activity of ppGalNAcT3 (unknown origin) using EA2 peptide as substrate incubated for 30 mins by HPLC-based enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 13(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of catalytic activity of ppGalNAcT13 (unknown origin) using EA2 peptide as substrate incubated for 30 mins by HPLC-based enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataKd:  294nMAssay Description:Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 14(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataIC50: 460nMAssay Description:Inhibition of catalytic activity of ppGalNAcT14 (unknown origin) using EA2 peptide as substrate incubated for 30 mins by HPLC-based enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataKi:  1.07E+3nMAssay Description:Competitive inhibition of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells using EA2 peptide as substrate by HPLC-based enzyme assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50215545(CHEMBL6338)
Affinity DataKi:  6.15E+3nMAssay Description:Non-competitive inhibition of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells using UDP-GalNAc as substrate by HPLC-based enzyme a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed