BDBM50215404 CHEMBL227235::[3-(2-iodo-6-methylaminopurin-9-yl)-2-phosphonomethylpropyl]-phosphonic acid

SMILES CNc1nc(I)nc2n(CC(CP(O)(O)=O)CP(O)(O)=O)cnc12

InChI Key InChIKey=GHMVWKJOLWGSGQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50215404   

TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215404([3-(2-iodo-6-methylaminopurin-9-yl)-2-phosphonomet...)
Affinity DataIC50: 790nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-induced inositol phosphate formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215404([3-(2-iodo-6-methylaminopurin-9-yl)-2-phosphonomet...)
Affinity DataIC50: 794nMAssay Description:Antagonist activity at human P2Y1 receptor expressed in 1321N1 cells assessed as inhibition of 2-MeS-ADP-stimulated PLC activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP2Y purinoceptor 1(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50215404([3-(2-iodo-6-methylaminopurin-9-yl)-2-phosphonomet...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]MRS-2270 from human P2Y1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed