BDBM50213730 (R)-2-amino-3-(diphenyl(4-(trifluoromethyl)phenyl)methylthio)propanoic acid::CHEMBL232133

SMILES N[C@@H](CSC(c1ccccc1)(c1ccccc1)c1ccc(cc1)C(F)(F)F)C(O)=O

InChI Key InChIKey=WUMHPVXOKHPCMF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50213730   

TargetKinesin-like protein KIF11(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50213730((R)-2-amino-3-(diphenyl(4-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 262nMAssay Description:Inhibition of His-tagged KSP motor domain (1 to 369) (unknown origin) assessed as inhibition of microtubule-stimulated KSP ATPase activity preincuabt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2016
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50213730((R)-2-amino-3-(diphenyl(4-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 220nMAssay Description:Inhibition of Eg5 assessed as inhibition ATP hydrolysis by ATPase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50213730((R)-2-amino-3-(diphenyl(4-(trifluoromethyl)phenyl)...)
Affinity DataIC50: 116nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 microtubule-stimulated ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed