BDBM50213105 (S,S)-(+)-5-[1-hydroxy-2-(1-methylhexylamino)ethyl]-1,3-benzenediol::CHEMBL389734::US10617654, Compound (S,S)-6

SMILES CCCC[C@H](C)NC[C@@H](O)c1cc(O)cc(O)c1

InChI Key InChIKey=HJBVVZKHZKVCCY-UHFFFAOYSA-N

Data  4 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50213105   

TargetBeta-2 adrenergic receptor(Human)
Department Of Health and Human Services

US Patent
LigandPNGBDBM50213105((S,S)-(+)-5-[1-hydroxy-2-(1-methylhexylamino)ethyl...)
Affinity DataKd:  5.62E+4nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
Go to US Patent

TargetBeta-1 adrenergic receptor(Rat)
Medical University of Lublin

Curated by ChEMBL
LigandPNGBDBM50213105((S,S)-(+)-5-[1-hydroxy-2-(1-methylhexylamino)ethyl...)
Affinity DataKi:  5.26E+4nMAssay Description:Displacement of [3H]CGP-12177 from beta-1 adrenergic receptor in Sprague-Dawley rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Department Of Health and Human Services

US Patent
LigandPNGBDBM50213105((S,S)-(+)-5-[1-hydroxy-2-(1-methylhexylamino)ethyl...)
Affinity DataKi:  5.62E+4nMAssay Description:Displacement of [3H]CGP12177 from human beta-2 adrenergic receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Mouse)
Department Of Health and Human Services

US Patent
LigandPNGBDBM50213105((S,S)-(+)-5-[1-hydroxy-2-(1-methylhexylamino)ethyl...)
Affinity DataKi:  5.26E+7nMAssay Description:β1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
Go to US Patent

TargetBeta-2 adrenergic receptor(Human)
Department Of Health and Human Services

US Patent
LigandPNGBDBM50213105((S,S)-(+)-5-[1-hydroxy-2-(1-methylhexylamino)ethyl...)
Affinity DataKi:  5.64E+7nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
Go to US Patent