BDBM50213093 (1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidinyl)cyclohexane::CHEMBL229125

SMILES O=C1CCN(C1)[C@@H]1CCCC[C@H]1OCCc1cccc2ccccc12

InChI Key InChIKey=OCJAMRRVVABJIC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50213093   

LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human heart sodium channel Nav1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of rat potassium channel Kv2.1 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat potassium channel Kv4.2 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 5(Human)
Cardiome Pharma

Curated by ChEMBL
LigandPNGBDBM50213093((1R,2R)-1-(1-naphthalenethoxy)-2-(3-ketopyrrolidin...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human potassium channel Kv1.5 by patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed