BDBM50212827 CHEMBL3350189

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C(C)C)[C@@H](O)[C@H](O)[C@H](CC1CCCCC1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)COc1cccc2ccccc12)C(=O)NCc1ccccn1

InChI Key InChIKey=ZTKCGLWIXHAITR-UHFFFAOYSA-N

Data  9 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50212827   

TargetPol polyprotein(Human immunodeficiency virus 2)
University of California

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataIC50: 30nMAssay Description:Inhibition of HIV-2 protease in 5%DMSOMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataIC50: 1nMAssay Description:Inhibition of HIV-1 protease in 5%DMSOMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataIC50: 750nMAssay Description:Inhibition of HIV-1 protease in 10% fetal calf serum(FCS)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi: <1nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi: <1nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi: <1nMAssay Description:Tested for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of California

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi: <1nMAssay Description:Evaluated for inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi:  2nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to reninMore data for this Ligand-Target Pair
In DepthDetails Article

TargetGenome polyprotein(Human rhinovirus B)
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi:  30nMAssay Description:Tested for the inhibition of HIV-2 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article

TargetCathepsin E(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi:  142nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin EMore data for this Ligand-Target Pair
In DepthDetails Article

TargetPepsin A(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi:  265nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to pepsinMore data for this Ligand-Target Pair
In DepthDetails Article

TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for aspartyl protease inhibition selectivity relative to Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails Article