BDBM50212777 1-(3-amino-3-oxopropyl)-2-benzamido-N-cyclohexyl-N-methyl-1H-benzo[d]imidazole-5-carboxamide::CHEMBL234019

SMILES CN(C1CCCCC1)C(=O)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccccc3)nc2c1

InChI Key InChIKey=NSSNPHNDZBWWAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212777   

TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212777(1-(3-amino-3-oxopropyl)-2-benzamido-N-cyclohexyl-N...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212777(1-(3-amino-3-oxopropyl)-2-benzamido-N-cyclohexyl-N...)
Affinity DataIC50: 1.10E+4nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed