BDBM50212775 1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-methoxybenzamido)-N-methyl-1H-benzo[d]imidazole-5-carboxamide::CHEMBL234020

SMILES COc1ccc(cc1)C(=O)Nc1nc2cc(ccc2n1CCC(N)=O)C(=O)N(C)C1CCCCC1

InChI Key InChIKey=VYOIHSHYYYZOMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212775   

TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212775(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-methoxyb...)
Affinity DataIC50: 1.70E+4nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212775(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-methoxyb...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed