BDBM50212763 3-(3-aminopropyl)-N-cyclohexyl-N-methyl-2-(thiophene-2-carboxamido)-3H-benzo[d]imidazole-5-carboxamide::CHEMBL398999

SMILES CN(C1CCCCC1)C(=O)c1ccc2nc(NC(=O)c3cccs3)n(CCCN)c2c1

InChI Key InChIKey=MREFPWMRKNGHTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212763   

TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212763(3-(3-aminopropyl)-N-cyclohexyl-N-methyl-2-(thiophe...)
Affinity DataIC50: 2.00E+4nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212763(3-(3-aminopropyl)-N-cyclohexyl-N-methyl-2-(thiophe...)
Affinity DataIC50: 710nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed