BDBM50211943 CHEMBL3914213

SMILES COc1cccc2cc(CCc3c([nH]c(=O)[nH]c3=O)C(O)=O)ccc12

InChI Key InChIKey=HHXFXLCZLKQPGP-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211943   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50211943(CHEMBL3914213)
Affinity DataIC50: 21nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50211943(CHEMBL3914213)
Affinity DataKi:  1.03E+4nMAssay Description:Inhibition of human dihydroorotate dehydrogenase assessed as reduction in orotate production using L-dihydroorotate as substrate measured after 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed