BDBM50211499 (1S,3R)-N-[3,5-bis(trifluoromethyl)benzyl]-1-methyl-3-[(1R,3'R)-methyl-1'H-spiro[indene-1,4'-piperidin]-1'-yl]cyclopentanecarboxamide::CHEMBL226066

SMILES C[C@H]1CN(CC[C@@]11C=Cc2ccccc12)[C@@H]1CC[C@@](C)(C1)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=UAKDPJAUOVRMIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211499   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211499((1S,3R)-N-[3,5-bis(trifluoromethyl)benzyl]-1-methy...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125]hMCP1 from human CCR2 receptor expressed in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211499((1S,3R)-N-[3,5-bis(trifluoromethyl)benzyl]-1-methy...)
Affinity DataIC50: 630nMAssay Description:Displacement of MIP1alpha from CCR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50211499((1S,3R)-N-[3,5-bis(trifluoromethyl)benzyl]-1-methy...)
Affinity DataIC50: 130nMAssay Description:Displacement of [125]hMCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed