BDBM50210299 6-(2-(4-methylpiperazin-1-yl)ethyl)-3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole::CHEMBL390353

SMILES CN1CCN(CCc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1

InChI Key InChIKey=XJODRXDUZDKWPQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210299   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210299(6-(2-(4-methylpiperazin-1-yl)ethyl)-3-(5-(3-phenox...)
Affinity DataIC50: 58nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210299(6-(2-(4-methylpiperazin-1-yl)ethyl)-3-(5-(3-phenox...)
Affinity DataIC50: 5nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210299(6-(2-(4-methylpiperazin-1-yl)ethyl)-3-(5-(3-phenox...)
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of hERG expressed in HEK293 cells assessed as effect on ionic current by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed