BDBM50208148 CHEMBL3891920::US9708270, 7

SMILES OC(=O)CC1CCC2(CC1)CCN(CC2)c1cc(OC(F)(F)F)ccc1F

InChI Key InChIKey=OBTYEVSIGAFZBO-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50208148   

TargetFree fatty acid receptor 4(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50208148(US9708270, 7 | CHEMBL3891920)
Affinity DataEC50:  49nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50208148(US9708270, 7 | CHEMBL3891920)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50208148(US9708270, 7 | CHEMBL3891920)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50208148(US9708270, 7 | CHEMBL3891920)
Affinity DataEC50:  700nMAssay Description:Agonist activity at ARMS2-PK2 -tagged human GPR120 short isoform expressed in CHOK1 cells assessed as induction of beta-arrestin2 recruitment after 9...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50208148(US9708270, 7 | CHEMBL3891920)
Affinity DataEC50:  470nMAssay Description:Agonist activity at mouse GPR120 expressed in U2OS cells assessed as induction of beta-arrestin2 recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50208148(US9708270, 7 | CHEMBL3891920)
Affinity DataEC50:  410nMAssay Description:On the day before the measurement day, CHO cells expressing human GPR120 were plated at 10000 cells per well in a 384-well black plate (#3702, Cornin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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