BDBM50207434 CHEMBL3981625

SMILES CN1CCN(CC1)C(=O)CNc1nc(c(s1)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=NSGSIJZIRIBNEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207434   

TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50207434(CHEMBL3981625)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in oxidation of TMPD using arachidonic acid as substrate preincubated for 5 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50207434(CHEMBL3981625)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in oxidation of TMPD using arachidonic acid as substrate preincubated for 5 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed