BDBM50206819 CHEMBL3893914

SMILES Cc1cc(Nc2cc(C)c(C#N)c(NCCOc3ccc(C)nc3)n2)n[nH]1

InChI Key InChIKey=BOWYXGHFMQMXPT-UHFFFAOYSA-N

Data  9 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50206819   

TargetCytochrome P450 2C19(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetRas-related protein Rab-7L1(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataKi:  4nMAssay Description:Inhibition of Aurora 2 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataKi:  4nMAssay Description:Inhibition of recombinant Aurora A kinase derived from human Hela cells using kemptide as substrate in presence of [c-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataKi:  10nMAssay Description:Inhibition of Aurora 1 kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataKi:  79nMAssay Description:Inhibition of YES (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataKi:  80nMAssay Description:Inhibition of FYN (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataKi:  80nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataKi:  480nMAssay Description:Inhibition of cSRC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Cxs

Curated by ChEMBL
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataKi:  490nMAssay Description:Inhibition of LYN (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed
LigandPNGBDBM50206819(CHEMBL3893914)
Affinity DataKi:  590nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2018
Entry Details Article
PubMed