BDBM50206578 CHEMBL222301::cis-((+/-)-Methyl(1R,2S/1S,2R)-2-[(4-Hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate::methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperidin-1-yl)-methyl]-1-(4-methylphenyl)cyclopropanecarboxylate

SMILES COC(=O)C1(CC1CN1CCC(O)(CC1)c1ccccc1)c1ccc(C)cc1

InChI Key InChIKey=BDSYECBSUUOPCT-UHFFFAOYSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50206578   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig brain sigma 1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H](+)-pentazocine from guinea pig sigma1 opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.29E+3nMAssay Description:Displacement of [3H]spiperone from rat striatum dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.42E+3nMAssay Description:Displacement of [3H]pyrilamine from rat cortex histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  3.15E+3nMAssay Description:Displacement of [3H]ketanserin from rat cortex 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  4.36E+3nMAssay Description:Displacement of [3H]mesulergine from guinea pig cortex 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of [3H]7OH-DPAT from rat olfactory tubercle dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]GR-13808 from guinea pig cortex 5HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]citalopram from rat cortex SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH-23390 from rat striatum dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LY278584 from rat cortex 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]WIN-35428 from rat striatum DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50206578(methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperid...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5HT from rat cloned 5HT6 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed