BDBM50206519 CHEMBL3735206

SMILES CC(C)(C)OC(=O)N1C[C@H](C[C@H]1C(=O)N[C@@H](Cc1ccc(Br)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)c(c1)[N+]([O-])=O)Oc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=DVYWYLGUYGYLRO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50206519   

LigandPNGBDBM50206519(CHEMBL3735206)
Affinity DataKi:  530nMAssay Description:Inhibition of 5-FAM-QEDIIRNIARHLAQVGDSMDRSIPPG binding to Mcl-1 (unknown origin) preincubated for 30 mins followed by FAM-labeled peptide addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
LigandPNGBDBM50206519(CHEMBL3735206)
Affinity DataKi:  530nMAssay Description:Competitive binding affinity to Mcl-1 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50206519(CHEMBL3735206)
Affinity DataKi:  930nMAssay Description:Competitive binding affinity to Bcl-2 (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50206519(CHEMBL3735206)
Affinity DataKi:  2.20E+3nMAssay Description:Competitive binding affinity to Bcl-XL (unknown origin) using 5-FAM-Bid-BH3 peptide preincubated for 30 mins before 5-FAM-Bid-BH3 peptide addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed