BDBM50206237 6-(4-chlorophenyl)-9-(3-(piperidin-1-yl)propoxy)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline::CHEMBL391062
SMILES Clc1ccc(cc1)C1CN2CCCC2c2cc(OCCCN3CCCCC3)ccc12
InChI Key InChIKey=QQWLHACUUDXPDH-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50206237
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rat)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]citalopram from rat brain SERTMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: 7.30nMAssay Description:Displacement of N-[3H]-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair