BDBM50205238 3-(2'-deoxy-beta-D-ribofuranosyl)-6-(2-fluorophenyl)-2,3-dihydrofuro[2,3-d]pyrimidin-2-one::CHEMBL376642

SMILES OC[C@H]1OC(C[C@@H]1O)n1cc2cc(oc2nc1=O)-c1ccccc1F

InChI Key InChIKey=FHXCFKUCSQESHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205238   

TargetThymidine kinase(HHV-1)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205238(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(2-fluoropheny...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant HSV-1 TK assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50205238(3-(2'-deoxy-beta-D-ribofuranosyl)-6-(2-fluoropheny...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant cytosolic TK-1 assessed as [CH3-H3]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed