BDBM50204492 1-(5-(2,4-dimethoxypyrimidin-5-yl)oxazol-2-yl)-7-phenylheptan-1-one::CHEMBL376201

SMILES COc1ncc(-c2cnc(o2)C(=O)CCCCCCc2ccccc2)c(OC)n1

InChI Key InChIKey=SJMDEKOYAAGHHD-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204492   

TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204492(1-(5-(2,4-dimethoxypyrimidin-5-yl)oxazol-2-yl)-7-p...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204492(1-(5-(2,4-dimethoxypyrimidin-5-yl)oxazol-2-yl)-7-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204492(1-(5-(2,4-dimethoxypyrimidin-5-yl)oxazol-2-yl)-7-p...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50204492(1-(5-(2,4-dimethoxypyrimidin-5-yl)oxazol-2-yl)-7-p...)
Affinity DataKi:  26nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdownMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed