BDBM50204371 2-{isopropoxy[(4-methoxyphenyl)sulfonyl]amino}-N-hydroxyacetamide::CHEMBL226439::N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonamido)acetamide

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)OC(C)C

InChI Key InChIKey=ICISPHGVMHWYTI-UHFFFAOYSA-N

Data  3 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50204371   

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataKi:  91nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50204371(N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonami...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 by CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed