BDBM50204103 CHEMBL3937311

SMILES N#CCc1ccc(Nc2ncnc3ccc(cc23)-c2ccccc2)cc1

InChI Key InChIKey=FSQLCPIRMDMFRQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50204103   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50204103(CHEMBL3937311)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using diC8 PIP2 as substrate after 60 mins by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50204103(CHEMBL3937311)
Affinity DataIC50: 6.95E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using diC8 PIP2 as substrate after 75 mins by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50204103(CHEMBL3937311)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using diC8 PIP2 as substrate after 120 mins by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Csir-Indian Institute of Integrative Medicine

Curated by ChEMBL
LigandPNGBDBM50204103(CHEMBL3937311)
Affinity DataIC50: 475nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using diC8 PIP2 as substrate after 80 mins by ADP-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2018
Entry Details Article
PubMed