BDBM50203995 (+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]piperazine trihydrochloride::CHEMBL537873

SMILES CC(C)N1CCC(CC1)C(CN1CCN(CCCc2cccc(F)c2-c2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=QZSJYHCBUZIVJV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50203995   

TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 482nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 3.94E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 3.13E+3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203995((+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-...)
Affinity DataIC50: 19.8nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed