BDBM50203993 (+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]-4-[4-(2-methoxy-1-naphthyl)butyl]piperazine trihydrochloride::CHEMBL558789

SMILES COc1ccc2ccccc2c1CCCCN1CCN(CC(C2CCN(CC2)C(C)C)c2ccc(F)cc2)CC1

InChI Key InChIKey=YQAIQMBVUVSWQU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50203993   

TargetMelanocortin receptor 4(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 40.3nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alphaMSH from human MC4R expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 877nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]pyrilamine from histamine H1 receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 2.83E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203993((+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed