BDBM50203986 2,2',4,4',6'-pentahydroxychalcone::CHEMBL244249

SMILES Oc1ccc(\C=C\C(=O)c2c(O)cc(O)cc2O)c(O)c1

InChI Key InChIKey=MDRJIGPMMMALHB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50203986   

TargetPolyphenol oxidase 2(White button mushroom)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50203986(2,2',4,4',6'-pentahydroxychalcone | CHEMBL244249)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50203986(2,2',4,4',6'-pentahydroxychalcone | CHEMBL244249)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in diphenolase activity using L-DOPA substrate pre-incubated for 20 mins at 30 degCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50203986(2,2',4,4',6'-pentahydroxychalcone | CHEMBL244249)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed