BDBM50203963 CHEMBL3907881

SMILES O=C(CC1NC(=O)NC1=O)N1CCN(CC1)c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1

InChI Key InChIKey=VWBKACQMUXNUJT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50203963   

TargetNeutrophil collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203963(CHEMBL3907881)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203963(CHEMBL3907881)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203963(CHEMBL3907881)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human AMPA-activated MMP2 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203963(CHEMBL3907881)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed