BDBM50203959 CHEMBL3955430

SMILES O=C(Cc1n[nH]c(=O)[nH]1)N1CCN(CC1)c1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1

InChI Key InChIKey=FMEMUXYNXWETSE-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50203959   

TargetCollagenase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of recombinant human AMPA-activated MMP13 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human AMPA-activated MMP9 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human AMPA-activated MMP2 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human AMPA-activated MMP3 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage metalloelastase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human AMPA-activated MMP12 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrilysin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human AMPA-activated MMP7 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human TACE using Cy3-PLAQAV(Cy5Q-L-2,3-diaminopropionic acid)-RSSSR-NH2 as substrate measured after 40 mins by spectrofluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of recombinant human AMPA-activated MMP10 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human AMPA-activated MMP1 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant human AMPA-activated MMP8 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203959(CHEMBL3955430)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of recombinant human GST-tagged MMP14 using Cy3-PLGLK(Cy5Q)AR-NH2 as substrate measured after 40 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed