BDBM50202467 CHEMBL3948663

SMILES O=C(CC#N)N1CCc2oc(cc2C1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key InChIKey=GGDYPNFYGKVTEZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50202467   

TargetTyrosine-protein kinase JAK3(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50202467(CHEMBL3948663)
Affinity DataIC50: 141nMAssay Description:Inhibition of GST-tagged recombinant human cytoplasmic JAK3 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Mouse)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50202467(CHEMBL3948663)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of JAK3 in mouse HT2 cells assessed as suppression of cell growthMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50202467(CHEMBL3948663)
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-tagged recombinant human JAK2 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50202467(CHEMBL3948663)
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of JAK2 in human TF1 cells assessed as suppression of cell growthMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed