BDBM50202420 CHEMBL219309::methyl 3,3'-difluoro-4'-{[({1-[(2,2,3,3,3-pentafluoropropanoyl)amino]cyclopropyl}carbonyl)amino]methyl}-1,1'-biphenyl-2-carboxylate

SMILES COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)C2(CC2)NC(=O)C(F)(F)C(F)(F)F)c(F)c1

InChI Key InChIKey=PYNIUHDPLMKGFJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202420   

TargetB2 bradykinin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202420(methyl 3,3'-difluoro-4'-{[({1-[(2,2,3,3,3-pentaflu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human bradykinin B2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetB1 bradykinin receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50202420(methyl 3,3'-difluoro-4'-{[({1-[(2,2,3,3,3-pentaflu...)
Affinity DataKi:  2.95nMAssay Description:Displacement of [3H]des-Arg10 Leu9 kallidin from human bradykinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed