BDBM50202404 (RR/SS)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine::(RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine::CHEMBL374634

SMILES CCCCC(C1CCCCN1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=CCEQAXVCJWOVQY-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50202404   

TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataIC50: 27nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataIC50: 27nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202404((RS/SR)-2-[1-(3,4-dichlorophenyl)pentyl]piperidine...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed