BDBM50202127 CHEMBL247746::N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)nicotinamide

SMILES Clc1ccc(NC(=O)c2cccnc2)c(CN2C(=O)c3ccccc3C2=O)c1

InChI Key InChIKey=VYWADYKBCDKIHN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202127   

TargetMetabotropic glutamate receptor 5(Rat)
Merck

Curated by ChEMBL
LigandPNGBDBM50202127(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202127(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50:  3.50E+4nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed