BDBM50201907 CHEMBL3940537

SMILES Cc1cnc(Nc2ccc(cc2)N2CCOCC2)nc1-c1cc2CN(CCc2o1)S(C)(=O)=O

InChI Key InChIKey=YDZHOVOPBMIATL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50201907   

TargetTyrosine-protein kinase SYK(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50201907(CHEMBL3940537)
Affinity DataIC50: 50nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50201907(CHEMBL3940537)
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-tagged recombinant human cytoplasmic JAK3 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK3(Mouse)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50201907(CHEMBL3940537)
Affinity DataIC50: 848nMAssay Description:Inhibition of JAK3 in mouse HT2 cells assessed as suppression of cell growthMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50201907(CHEMBL3940537)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of GST-tagged recombinant human JAK2 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50201907(CHEMBL3940537)
Affinity DataIC50: 426nMAssay Description:Inhibition of JAK2 in human TF1 cells assessed as suppression of cell growthMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed