BDBM50201902 2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline-4-carboxylicacid::CHEMBL267210

SMILES Cc1ccc2c(C(O)=O)c(O)c(nc2c1C)-c1ccc(Cl)cc1

InChI Key InChIKey=BVCMDMYFMGSYTP-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50201902   

TargetCytochrome P450 2A6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2A6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin glycoprotein ligand 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibition of P-selectin-mediated adhesion of HL60 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed