BDBM50201813 CHEMBL584338

SMILES CC1(C)OC2=C(C1Nc1ccc(F)c(c1)[N+]([O-])=O)C(=O)C(=O)c1ccccc21

InChI Key InChIKey=HMKIICIVRKQVLD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201813   

TargetNAD(P)H dehydrogenase [quinone] 1(Human)
Federal University of Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50201813(CHEMBL584338)
Affinity DataIC50: 3.20E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days in presence of NQO1 inhibitor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
Federal University of Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50201813(CHEMBL584338)
Affinity DataIC50: 1.30E+3nMAssay Description:Activation of NQO1 in human A549 cells assessed as decrease in cell survival incubated for 2 hrs measured after 7 days by Hoechst 33258 staining base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2018
Entry Details Article
PubMed