BDBM50201701 CHEMBL390474::cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3.2.1]octan-7-one

SMILES Cc1cccc(O[C@H]2CCN3C[C@H]2OC3=O)c1C

InChI Key InChIKey=SIIJWJNEODXHNY-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50201701   

TargetDipeptidyl peptidase 1(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201701(cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3....)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPro-cathepsin H(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201701(cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3....)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of human recombinant cathepsin HMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201701(cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3....)
Affinity DataIC50: 197nMAssay Description:Inhibition of human recombinant cathepsin XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201701(cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3....)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201701(cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3....)
Affinity DataIC50: 131nMAssay Description:Inhibition of human recombinant cathepsin VMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201701(cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3....)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201701(cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3....)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201701(cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3....)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin F(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201701(cis-4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3....)
Affinity DataIC50: 331nMAssay Description:Inhibition of human recombinant cathepsin FMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed