BDBM50201286 CHEMBL233201::N,N-dimethyl-3-((2-(tetrahydro-2H-thiopyran-4-yl)ethylamino)methyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepin-3-amine

SMILES CN(C)C1(CNCCC2CCSCC2)COc2ccccc2OC1

InChI Key InChIKey=MMHVHROUFYSFCY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201286   

TargetMuscarinic acetylcholine receptor M3(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201286(N,N-dimethyl-3-((2-(tetrahydro-2H-thiopyran-4-yl)e...)
Affinity DataKi:  6.80nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201286(N,N-dimethyl-3-((2-(tetrahydro-2H-thiopyran-4-yl)e...)
Affinity DataKi:  7.20nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50201286(N,N-dimethyl-3-((2-(tetrahydro-2H-thiopyran-4-yl)e...)
Affinity DataKi:  52nMAssay Description:Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed