BDBM50200539 CHEMBL3925858

SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCNCC2)CC1

InChI Key InChIKey=BTNNIEZIMHCWOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50200539   

TargetALK tyrosine kinase receptor(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200539(CHEMBL3925858)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant wild type ALK (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed