BDBM50200537 CHEMBL3736267

SMILES CC1(C)c2[nH]c3cc(ccc3c2C(=O)c2ccc(cc12)C1CCN(CC2(O)CCOCC2)CC1)C#N

InChI Key InChIKey=GQCZYWQBXDXVLF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50200537   

TargetALK tyrosine kinase receptor(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200537(CHEMBL3736267)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant wild type ALK (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200537(CHEMBL3736267)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200537(CHEMBL3736267)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant ALK (unknown origin) using poly (Glu, Tyr)4:1 substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200537(CHEMBL3736267)
Affinity DataIC50: 100nMAssay Description:Inhibition of gatekeeper ALK L1196M mutant (unknown origin) using poly (Glu, Tyr)4:1 substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed