BDBM50200534 CHEMBL3958173

SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCN(CC2(O)CCOCC2)CC1

InChI Key InChIKey=BLTNVYOBZUELAP-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50200534   

TargetVascular endothelial growth factor receptor 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant ABL (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant c-Kit (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant wild type ALK (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant PDGFR-alpha (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant IGF1R (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant ErbB2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant c-Src (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant EPHA2 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant PDGFR-beta (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant ErbB4 (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50200534(CHEMBL3958173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant EGFR (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed