BDBM50199407 CHEMBL3902668::US10131658, Compound 202

SMILES NC(=N)N[C@H]1CC[C@H](CC1)C(=O)Nc1ccc(C[C@H](NC(=O)[C@@H]2CCCN2S(=O)(=O)c2ccccc2)C(O)=O)cc1

InChI Key InChIKey=XFHCUQCLLGVBIK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199407   

TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50199407(CHEMBL3902668 | US10131658, Compound 202)
Affinity DataIC50: 2nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50199407(CHEMBL3902668 | US10131658, Compound 202)
Affinity DataIC50: 2nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1 [T112H](Human)
University of California

US Patent
LigandPNGBDBM50199407(CHEMBL3902668 | US10131658, Compound 202)
Affinity DataIC50: 505nMAssay Description:A panel of cell lines and integrin ligands were developed to allow rapid examination of potency and specificity of inhibitors against all 8 integrins...More data for this Ligand-Target Pair
In DepthDetails
US Patent