BDBM50199401 CHEMBL3970391::US10131658, Compound 204

SMILES Cc1ccc(NCCCC(=O)Nc2ccc(C[C@H](NC(=O)[C@@H]3CCCN3S(=O)(=O)c3ccccc3)C(O)=O)cc2)nc1

InChI Key InChIKey=BIWLMYQUTFMBFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199401   

TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50199401(CHEMBL3970391 | US10131658, Compound 204)
Affinity DataIC50: 320nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50199401(CHEMBL3970391 | US10131658, Compound 204)
Affinity DataIC50: 316nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIntegrin alpha-5/beta-1 [T112H](Human)
The Regents of The University of California

US Patent
LigandPNGBDBM50199401(CHEMBL3970391 | US10131658, Compound 204)
Affinity DataIC50: 505nMAssay Description:A panel of cell lines and integrin ligands were developed to allow rapid examination of potency and specificity of inhibitors against all 8 integrins...More data for this Ligand-Target Pair
In DepthDetails
US Patent