BDBM50199119 CHEMBL3948452

SMILES CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(\C=C\C(=O)Nc2ccccc2N)c(F)c1

InChI Key InChIKey=LPHGULGLUJFAAG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50199119   

TargetHistone deacetylase 3(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199119(CHEMBL3948452)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of HDAC3 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199119(CHEMBL3948452)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199119(CHEMBL3948452)
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199119(CHEMBL3948452)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199119(CHEMBL3948452)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed