BDBM50199113 CHEMBL3955013

SMILES CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(C(=O)Nc2ccccc2N)c(F)c1

InChI Key InChIKey=PJRDOAZAXZZNAM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50199113   

TargetAndrogen receptor(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199113(CHEMBL3955013)
Affinity DataIC50: 330nMAssay Description:Displacement of [3H]mibolerone from androgen receptor (unknown origin) in membranes after 24 hrs by HAP adsorption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199113(CHEMBL3955013)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199113(CHEMBL3955013)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of HDAC2 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199113(CHEMBL3955013)
Affinity DataIC50: 4.73E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199113(CHEMBL3955013)
Affinity DataIC50: 6.19E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) assessed as inhibition of fluorogenic peptide deacetylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2018
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199113(CHEMBL3955013)
Affinity DataIC50: 1.70E+3nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50199113(CHEMBL3955013)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed