BDBM50199071 2-(2,3-dihydroxypropyl)-4-(3-fluorophenyl)-6-methoxy-1-oxo-1,2-dihydroisoquinoline-3-carbonitrile::CHEMBL215023

SMILES COc1ccc2c(c1)c(-c1cccc(F)c1)c(C#N)n(CC(O)CO)c2=O

InChI Key InChIKey=BUXRKQONBGINRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199071   

TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199071(2-(2,3-dihydroxypropyl)-4-(3-fluorophenyl)-6-metho...)
Affinity DataIC50: 870nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199071(2-(2,3-dihydroxypropyl)-4-(3-fluorophenyl)-6-metho...)
Affinity DataIC50: 3.35E+4nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed