BDBM50199070 2-[(2S)-2,3-dihydroxypropyl]-6-methoxy-1-oxo-4-phenyl-1,2-dihydroisoquinoline-3-carbonitrile::CHEMBL216894

SMILES COc1ccc2c(c1)c(-c1ccccc1)c(C#N)n(C[C@H](O)CO)c2=O

InChI Key InChIKey=IHNXTAHQOZPVBI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199070   

TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199070(2-[(2S)-2,3-dihydroxypropyl]-6-methoxy-1-oxo-4-phe...)
Affinity DataIC50: 1.01E+3nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199070(2-[(2S)-2,3-dihydroxypropyl]-6-methoxy-1-oxo-4-phe...)
Affinity DataIC50: 1.35E+5nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed