BDBM50199063 4-(3-fluorophenyl)-6-methoxy-2-{2-[(2-methoxyethyl)(methyl)amino]ethyl}-1-oxo-1,2-dihydroisoquinoline-3-carbonitrile::CHEMBL215050

SMILES COCCN(C)CCn1c(C#N)c(-c2cccc(F)c2)c2cc(OC)ccc2c1=O

InChI Key InChIKey=WKPNRUNTHWRFNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199063   

TargetPotassium voltage-gated channel subfamily A member 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199063(4-(3-fluorophenyl)-6-methoxy-2-{2-[(2-methoxyethyl...)
Affinity DataIC50: 790nMAssay Description:Antagonist activity at human Kv1.5 channel expressed in CHO cell membrane by HT clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50199063(4-(3-fluorophenyl)-6-methoxy-2-{2-[(2-methoxyethyl...)
Affinity DataIC50: 1.65E+3nMAssay Description:Binding affinity to hERG potassium channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed